Some flights were more than two hours behind schedule. Airports around the South also reported delays and cancellations.
"If we don't deliver the resources, manpower, and technology the FAA it needs to upgrade the system, these technical glitches that cause cascading delays and chaos across the country are going to become a very regular occurrence," he said in a statement.
"We were going to be there for a four-day weekend, but now it's getting cut short," James said. "It's just not a good day."
"You have to wonder what's the glitch? Glitch is kind of a general term, it could encompass many, many things," he said. "So it is a concern, but I tend to be an optimist."
Passengers were asked to check the status of their flights online before going to airports.
It was reminiscent of a software malfunction that delayed hundreds of flights around the country in August 2008.
In that episode, the Northeast was hardest hit by the delays because of a glitch at the Hampton facility, which processes flight plans for the eastern half of the U.S.